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Diazepam is a benzodiazepine drug that is used to treat anxiety disorders, seizures, alcohol withdrawal symptoms, insomnia, muscle spasms, and panic attacks. Benzodiazepines work by increasing the effect of neurotransmitters in the brain. These drugs have been around since the 1950’s and are still widely prescribed today.
The exact mechanism of action of Diazepam is not fully understood, however it is believed that it works by binding to specific receptors in the brain. There are two types of benzodiazepine receptors that are located throughout the brain; these receptors are called GABA-A and GABAA receptors. When Diazepam binds to the GABA-A receptor, it increases the amount of chloride ions entering the neurons. This causes hyperpolarization of the neuron membrane, which decreases the release of excitatory neurotransmitters (glutamate) and inhibits nerve impulses. Diazepam also binds to the GABAA receptor, which results in increased inhibition of the central nervous system.
Benzodiazepines are commonly prescribed to treat anxiety disorders, including generalized anxiety disorder, panic disorder, social phobia, posttraumatic stress disorder, and obsessive compulsive disorder. Other uses include treating insomnia, muscle spasms and tremors, and alcohol withdrawal symptoms.
Some side effects associated with Diazepam include dizziness, dry mouth, headache, nausea, vomiting, and tachycardia. If you experience any of these side effects while taking Diazepam, stop using the medication immediately and consult your doctor.
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